rhBMP-4 (500 UG)-细胞因子-2D/3D培养-优宁维细胞/细胞培养平台
rhBMP-4 (500 UG)
货号: 314-BP-500 品牌: R&D Systems
规格: 500UG
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价格: ¥ 41371.00

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概述
别名
BMP-2B; BMP2B1; BMP2BMCOPS6; BMP4; BMP-4; Bone morphogenetic protein 2B; bone morphogenetic protein 4; DVR4; OFC11; ZYME
全称
Bone Morphogenetic Protein 4
形式
Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
是否允许进口
允许
是否危险品
非危险品
性能
供应商
R&D Systems
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Directed Differentiation of Human Induced Pluripotent Stem Cells into Fallopian Tube Epithelium
Authors: N Yucer, M Holzapfel, T Jenkins Vo, L Lenaeus, L Ornelas, A Laury, D Sareen, R Barrett, BY Karlan, CN Svendsen
Sci Rep, 2017;7(1):10741.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Gelatin device for the delivery of growth factors involved in endochondral ossification
Authors: LA Ahrens, D Vonwil, J Christense, VP Shastri
PLoS ONE, 2017;12(4):e0175095.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
In Vitro Micropatterned Human Pluripotent Stem Cell Test (�P-hPST) for Morphometric-Based Teratogen Screening
Authors: J Xing, Y Cao, Y Yu, H Li, Z Song, H Yu
Sci Rep, 2017;7(1):8491.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1?
Authors: KM Tsang, JS Hyun, KT Cheng, M Vargas, D Mehta, M Ushio-Fuka, L Zou, KV Pajcini, J Rehman, AB Malik
Stem Cell Reports, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Supraphysiological levels of GDF11 induce striated muscle atrophy
Authors: DW Hammers, M Merscham-B, JY Hsiao, S Engst, JJ Hartman, HL Sweeney
EMBO Mol Med, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
Authors: F Sampazioti, MC de Brito, I Geti, A Bertero, NR Hannan, L Vallier
Nat Protoc, 2017;12(4):814-827.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling
Authors: KB McCauley, F Hawkins, M Serra, DC Thomas, A Jacob, DN Kotton
Cell Stem Cell, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency
Authors: JH Lee, S Laronde, TJ Collins, Z Shapovalov, B Tanasijevi, JD McNicol, A Fiebig-Com, YD Benoit, JB Lee, RR Mitchell, M Bhatia
Cell Rep, 2017;19(1):20-35.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection
Authors: F Sakurai, S Mitani, T Yamamoto, K Takayama, M Tachibana, K Watashi, T Wakita, S Iijima, Y Tanaka, H Mizuguchi
Sci Rep, 2017;7(0):45698.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Physico-electrochemical Characterization of Pluripotent Stem Cells during Self-Renewal or Differentiation by a Multi-modal Monitoring System
Authors: K Low, LY Wong, M Maldonado, C Manjunath, CB Horner, M Perez, NV Myung, J Nam
Stem Cell Reports, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations
Authors: JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller
Cell Stem Cell, 2017;21(2):179-194.e4.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Highly Efficient Differentiation of Endothelial Cells from Pluripotent Stem Cells Requires the MAPK and the PI3K Pathways
Authors: A Harding, E Cortez-Tol, NL Magner, JR Beegle, DP Coleal-Ber, D Hao, A Wang, JA Nolta, P Zhou
Stem Cells, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
Authors: AG Kotini, CJ Chang, A Chow, H Yuan, TC Ho, T Wang, S Vora, A Solovyov, C Husser, M Olszewska, J Teruya-Fel, D Perumal, VM Klimek, A Spyridonid, RK Rampal, L Silverman, EP Reddy, E Papaemmanu, S Parekh, BD Greenbaum, CS Leslie, MG Kharas, EP Papapetrou
Cell Stem Cell, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
In�Vitro Modeling of Blood-Brain Barrier with Human iPSC-Derived Endothelial Cells, Pericytes, Neurons, and Astrocytes via Notch Signaling
Authors: K Yamamizu, M Iwasaki, H Takakubo, T Sakamoto, T Ikuno, M Miyoshi, T Kondo, Y Nakao, M Nakagawa, H Inoue, JK Yamashita
Stem Cell Reports, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity
Authors: Y Choudhury, YC Toh, J Xing, Y Qu, J Poh, L Huan, HS Tan, R Kanesvaran, H Yu, MH Tan
Sci Rep, 2017;7(0):41238.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Wnt/?-catenin promotes gastric fundus specification in mice and humans
Authors: KW McCracken, E Aihara, B Martin, CM Crawford, T Broda, J Treguier, X Zhang, JM Shannon, MH Montrose, JM Wells
Nature, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-?2 in Human TM Cells
Authors: AA Mody, RJ Wordinger, AF Clark
Invest. Ophthalmol. Vis. Sci, 2017;58(2):849-859.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells
Nat Protoc, 2017;12(1):15-31.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Thrombospondin-1 (TSP-1), a new bone morphogenetic protein-2 and -4 (BMP-2/4) antagonist identified in pituitary cells
Authors: C Sallon, I Callebaut, I Boulay, J Fontaine, D Logeart-Av, C Henriquet, M Pugnière, X Cayla, P Monget, G Harichaux, V Labas, S Canepa, C Taragnat
J. Biol. Chem., 2017;0(0):.
Species: Human
Sample Type: Recombinant Protein
Application: Bioassay
Integrated RNA-seq and DNase-seq analyses identify phenotype-specific BMP4 signaling in breast cancer
Authors: M Ampuja, T Rantapero, A Rodriguez-, M Palmroth, EL Alarmo, M Nykter, A Kallioniem
BMC Genomics, 2017;18(1):68.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics
Authors: NG Kooreman, PE de Almeida, JP Stack, RV Nelakanti, S Diecke, NY Shao, RJ Swijnenbur, V Sanchez-Fr, E Matsa, C Liu, AJ Connolly, JF Hamming, PHA Quax, MA Brehm, DL Greiner, LD Shultz, JC Wu
Cell Rep, 2017;20(8):1978-1990.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Bone morphogenetic protein signaling mediated by ALK-2 and DLX2 regulates apoptosis in glioma-initiating cells
Authors: E Raja, A Komuro, R Tanabe, S Sakai, Y Ino, N Saito, T Todo, M Morikawa, H Aburatani, D Koinuma, C Iwata, K Miyazono
Oncogene, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells
Authors: D Jung, J Xiong, M Ye, X Qin, L Li, S Cheng, M Luo, J Peng, J Dong, F Tang, W Shen, MM Matzuk, K Kee
Nat Commun, 2017;8(0):15680.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Expression of the Human Herpesvirus 6A Latency-Associated Transcript U94A Disrupts Human Oligodendrocyte Progenitor Migration
Authors: A Campbell, JM Hogestyn, CJ Folts, B Lopez, C Pröschel, D Mock, M Mayer-Prös
Sci Rep, 2017;7(1):3978.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Lipopolysaccharides induced inflammatory responses and electrophysiological dysfunctions in human-induced pluripotent stem cell derived cardiomyocytes
Authors: G Yücel, Z Zhao, I El-Battraw, H Lan, S Lang, X Li, F Buljubasic, WH Zimmermann, L Cyganek, J Utikal, U Ravens, T Wieland, M Borggrefe, XB Zhou, I Akin
Sci Rep, 2017;7(1):2935.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Induced pluripotent stem cell-derived limbal epithelial cells (LiPSC) as a cellular alternative for in vitro ocular toxicity testing
Authors: E Aberdam, I Petit, L Sangari, D Aberdam
PLoS ONE, 2017;12(6):e0179913.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols
Authors: D Jeziorowsk, V Fontaine, C Jouve, E Villard, S Dussaud, D Akbar, V Letang, P Cervello, JM Itier, MP Pruniaux, JS Hulot
Int J Mol Sci, 2017;18(6):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate
Authors: AG Freire, A Waghray, F Soares-da-, TP Resende, DF Lee, CF Pereira, DS Nascimento, IR Lemischka, P Pinto-do-Ó
Stem Cell Reports, 2017;0(0):.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Fetal Therapy Model of Myelomeningocele with Three-Dimensional Skin Using Amniotic Fluid Cell-Derived Induced Pluripotent Stem Cells
Authors: K Kajiwara, T Tanemoto, S Wada, J Karibe, N Ihara, Y Ikemoto, T Kawasaki, Y Oishi, O Samura, K Okamura, S Takada, H Akutsu, H Sago, A Okamoto, A Umezawa
Stem Cell Reports, 2017;8(6):1701-1713.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Induction of senescence in primary glioblastoma cells by serum and TGF?
Authors: R Kumar, A Gont, TJ Perkins, JEL Hanson, IAJ Lorimer
Sci Rep, 2017;7(1):2156.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Differentiation of cardiomyocytes and generation of human engineered heart tissue
Authors: K Breckwoldt, D Letuffe-Br, I Mannhardt, T Schulze, B Ulmer, T Werner, A Benzin, B Klampe, MC Reinsch, S Laufer, A Shibamiya, M Prondzynsk, G Mearini, D Schade, S Fuchs, C Neuber, E Krämer, U Saleem, ML Schulze, ML Rodriguez, T Eschenhage, A Hansen
Nat Protoc, 2017;12(6):1177-1197.
Species: Human
Sample Type: Whole Tissue
Application: Bioassay
Recapitulating and Correcting Marfan Syndrome in a Cellular Model
Authors: JW Park, L Yan, C Stoddard, X Wang, Z Yue, L Crandall, T Robinson, Y Chang, K Denton, E Li, B Jiang, Z Zhang, K Martins-Ta, SP Yee, H Nie, F Gu, W Si, T Xie, L Yue, RH Xu
Int. J. Biol. Sci., 2017;13(5):588-603.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-? receptor type I ALK5
Authors: LK Bollum, K Huse, MP Oksvold, B Bai, VI Hilden, L Forfang, SO Yoon, S Wälchli, EB Smeland, JH Myklebust
PLoS ONE, 2017;12(5):e0177188.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Direct comparison of distinct naive pluripotent states in human embryonic stem cells
Authors: S Warrier, M Van der Je, G Duggal, L Tilleman, E Sutherland, J Taelman, M Popovic, S Lierman, S Chuva De S, A Van Soom, L Peelman, F Van Nieuwe, DIM De Coninck, B Menten, P Mestdagh, J Van de Som, D Deforce, P De Sutter, B Heindryckx
Nat Commun, 2017;8(0):15055.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Lineage commitment of embryonic cells involves MEK1-dependent clearance of pluripotency regulator Ventx2
Authors: P Scerbo, L Marchal, L Kodjabachi
Elife, 2017;6(0):.
Species: Xenopus
Sample Type: In Vivo
Application: In Vivo
Prospective isolation of NKX2-1-expressing human lung progenitors derived from pluripotent stem cells
Authors: F Hawkins, P Kramer, A Jacob, I Driver, DC Thomas, KB McCauley, N Skvir, AM Crane, AA Kurmann, AN Hollenberg, S Nguyen, BG Wong, AS Khalil, SX Huang, S Guttentag, JR Rock, JM Shannon, BR Davis, DN Kotton
J. Clin. Invest., 2017;127(6):2277-2294.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
A pluripotent stem cell-based model for post-implantation human amniotic sac development
Authors: Y Shao, K Taniguchi, RF Townshend, T Miki, DL Gumucio, J Fu
Nat Commun, 2017;8(1):208.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis
Authors: NJ Palpant, Y Wang, B Hadland, RJ Zaunbreche, M Redd, D Jones, L Pabon, R Jain, J Epstein, WL Ruzzo, Y Zheng, I Bernstein, A Margolin, CE Murry
Cell Rep, 2017;20(7):1597-1608.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence
Authors: N Rahman, PM Brauer, L Ho, T Usenko, M Tewary, JC Zúñiga-Pfl, PW Zandstra
Nat Commun, 2017;8(0):15380.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients
Elife, 2016;5(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway
Cell Biosci, 2016;6(1):50.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Heparin Promotes Cardiac Differentiation of Human Pluripotent Stem Cells in Chemically Defined Albumin-Free Medium, Enabling Consistent Manufacture of Cardiomyocytes
Stem Cells Transl Med, 2016;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
ROCK inhibitor primes human induced pluripotent stem cells to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation
Stem Cell Res, 2016;17(2):222-227.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Microfabric Vessels for Embryoid Body Formation and Rapid Differentiation of Pluripotent Stem Cells
Sci Rep, 2016;6(0):31063.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells
EMBO Mol Med, 2016;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Medial HOXA genes demarcate haematopoietic stem cell fate during human development
Nat Cell Biol, 2016;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease
Authors: Mariko Horii
Proc Natl Acad Sci USA, 2016;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes
Stem Cell Reports, 2016;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
MxA Is a Novel Regulator of Endosome-Associated Transcriptional Signaling by Bone Morphogenetic Proteins 4 and 9 (BMP4 and BMP9)
PLoS ONE, 2016;11(11):e0166382.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling
Stem Cell Res Ther, 2016;7(1):115.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Yes-Associated Protein Inhibits Transcription of Myocardin and Attenuates Differentiation of Vascular Smooth Muscle Cell from Cardiovascular Progenitor Cell Lineage
Stem Cells, 2016;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells
Nat Commun, 2016;7(0):13602.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves
EBioMedicine, 2016;10(0):282-90.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Sinoatrial node cardiomyocytes derived from human pluripotent cells function as a biological pacemaker
Nat. Biotechnol, 2016;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
The involvement of protein kinase C-? in isoflurane induced preconditioning of human embryonic stem cell--derived Nkx2.5(+) cardiac progenitor cells
Authors: IA Song, AY Oh, JH Kim, YM Choi, YT Jeon, JH Ryu, JW Hwang
BMC Anesthesiol, 2016;16(0):13.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
In�Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts
Authors: S Kadota, L Pabon, H Reinecke, CE Murry
Stem Cell Reports, 2016;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
Authors: N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, J Tchieu, MA Soliman, G Lee, JL Casanova, L Studer
Nat. Med., 2016;22(12):1421-1427.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer.
Authors: Hermanson D, Bendzick L, Pribyl L, McCullar V, Vogel R, Miller J, Geller M, Kaufman D
Stem Cells, 2016;34(1):93-101.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Tumor-Derived Factors and Reduced p53 Promote Endothelial Cell Centrosome Over-Duplication
PLoS ONE, 2016;11(12):e0168334.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Five colour variants of bright luminescent protein for real-time multicolour bioimaging
Nat Commun, 2016;7(0):13718.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
BMP4 depletion by miR-200 inhibits tumorigenesis and metastasis of lung adenocarcinoma cells.
Authors: Kim J, Kurie J, Ahn Y
Mol Cancer, 2015;14(1):173.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Improved hematopoietic differentiation efficiency of gene-corrected beta-thalassemia induced pluripotent stem cells by CRISPR/Cas9 system.
Authors: Song B, Fan Y, He W, Zhu D, Niu X, Wang D, Ou Z, Luo M, Sun X
Stem Cells Dev, 2015;24(9):1053-65.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile.
Authors: Sugawa F, Arauzo-Bravo M, Yoon J, Kim K, Aramaki S, Wu G, Stehling M, Psathaki O, Hubner K, Scholer H
EMBO J, 2015;34(8):1009-24.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis.
Authors: Kim M, Horst A, Blinka S, Stamm K, Mahnke D, Schuman J, Gundry R, Tomita-Mitchell A, Lough J
PLoS ONE, 2015;10(2):e0118670.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells.
Authors: Gori J, Butler J, Chan Y, Chandrasekaran D, Poulos M, Ginsberg M, Nolan D, Elemento O, Wood B, Adair J, Rafii S, Kiem H
J Clin Invest, 2015;125(3):1243-54.
Species: Primate - Macaca nemestrina (Southern Pig-tailed Macaque)
Sample Type: Whole Cells
Application: Bioassay
Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells.
Authors: Iyer D, Gambardella L, Bernard W, Serrano F, Mascetti V, Pedersen R, Talasila A, Sinha S
Development, 2015;142(8):1528-41.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells.
Authors: Lee J, Graham M, Collins T, Lee J, Hong S, McNicol A, Shapovalova Z, Bhatia M
Stem Cells, 2015;33(4):1142-52.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Generation of articu

参考图片

Recombinant Human BMP-4 (Catalog #
314-BP/CF) induces alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED50 for this effect is 2.5-15 ng/mL.

1 ug/lane of Recombinant Human BMP-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 22-25 kDa and 37-41 kDa, respectively. Multiple bands in gel are due to variable glycosylation.

 

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