货号： 130-093-435 品牌： Miltenyi 库存： 公司现货
PepTivator CMV pp65, human, 60nmol
PepTivator ® CMV pp65 is a peptide pool that consists mainly of 15-mer peptides with 11–amino acid (aa) overlap, covering the complete sequence of the pp65 protein of human cytomegalovirus (UniProt ID: P06725).PepTivator peptide pools have been developed for the efficient in vitro stimulation of antigen-specific CD4 + and CD8 + T cells, as peptides of 15–aa length with 11–aa overlap represent an optimized solution for stimulating both CD4 + and CD8 + T cells in various applications.Quantitative, phenotypical, or functional analysis of pp65-specific T cell immunity can provide important information on the natural course of immune responses in healthy or immunocompromised individuals.PepTivator CMV pp65-HT is a peptide pool lyophilized in the wells of a 96-well plate, allowing stimulation and analysis of cells directly on the plate. The convenient 96-well format, composed of 12 individually removable strips of 8 wells each allows for easy and flexible experimental set-up, different antigens can be combined by assembling different strips. A control can also be added easily by using strips from the Control plate (12x8).
CMV pp65 (65 kDa lower matrix phosphoprotein), also known as glycoprotein 64 or UL83, is a virion tegument protein and the main component of the enveloped subviral particle. CMV pp65 is an immunodominant target of CD4+ and CD8+ T cell responses to CMV. CMV pp65-specific T cells predominantly produce inflammatory cytokines, such as IFN-γ, IL-2, and TNF-α.